BEN BIKMAN a4 | DEPRESSION; ANXIETY: Better on Ketones
http://www.DoctorsToTrust.com
presents episode 2223 | DR BEN BIKMAN in InsulinIQ.com Metabolic Classroom
Atypical anti-depressant: Trazodone, also used for sleep
disorders...
-can have off target effect: increase prolactin
-my blood test: prolactin 10X normal!
-stopped the drug, prolactin levels slowly coming down
Trazodone acts as serotonin re-uptake inhibitor and
as serotonin to receptor antagonist
-helps with depression & anxiety
-and sedative effect
Very modest metabolic effect when used
at insomnia dosage
Many of these antidepressant and anxiety meds affect
regulation of hunger in brain...
-promote craving of carbs
Anxiety & depression share the foundational contributor:
brain glucose hypometabolism
-this also applies to Alzheimers, migraines,
epilepsy, depression, bi-polar, anxiety
All Share This:
Brain Unable to Use Glucose Effectively
One Common Contributor to all these:
Brain Is Going HUNGRY
Tragic because it is driven by IR of the brain...
-brain has some glucose transporters that are dependent
on insulin working well
Brain has 2 primary fuels: glucose & ketones
Ketones are very good fuel for brain...perhaps preferred
Suppose: glucose 5 mmol & ketones 2 mmol
Brain will get well over half of energy
from ketones: its preferred fuel
Research: ketones Up; mental health UP
-improved neurotransmitter balance
-and mitochondrial health and reduce IR
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original video interview: https://youtu.be/XJdFXCC7k7g?si=ZYi2Wuymz7QQPQkW
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