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BEN BIKMAN a1 | ANTIDEPRESSANT ALTERS BRAIN …serotonin actively STORES FAT & PREVENTS FAT BURNING
http://www.DoctorsToTrust.com
presents episode 2220 | DR BEN BIKMAN in InsulinIQ.com Metabolic Classroom
Effects on metabolic health of antidepressant &
anti-anxiety meds...
Mental health disorders, like depression & anxiety, are
tightly linked with metabolic conditions like insulin resistance
& its consequence: T2D
Depression can lead to metabolic disturbances, as well as,
metabolic issues can worsen mental
health conditions
Well known that myriad antidepressant & anti-anxiety meds
can lead to significant metabolic side effects,
like obesity & IR...
Key main neurotransmitters that are altered
-to create the problem, or
-to help solve the problem
1-serotonin [5HT] regulates mood, anxiety & overall feeling
of wellness
-low levels have been linked to depression & anxiety &
sleep disorders
If we stick with serotonin in central nervous system
-it has metabolic function: appetite
-contributes to appetite suppression
-acts like leptin, signals satiety
-signals cravings for carbs & sugars
Serotonin activates same regulator...
-can lead to greater fat storage &
-upregulation of the genes associated with the process
At same time: thru serotonin 2A receptors, can inhibit
lipolysis [breakdown of fat], so drives
fat cell to Continue to Store more fat
Serotonin prevents maturation of
brown fat cells
Serotonin inhibits thermogenesis
[mitochondrial uncoupling--revving the
engine, but not working]
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original video interview: https://youtu.be/XJdFXCC7k7g?si=ZYi2Wuymz7QQPQkW
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