A Mom Drank 3 Gallons Water In 2 Hours. This Is What Happened To Her Brain.

Details of this case are based on an event happening in 2007, some details changed in presentation to teach more about the pathophysiology and associated acute illness.

Music by Lifeformed: https://lifeformed.bandcamp.com/

Head MRI images by Professor Anastasios Karatopis https://youtu.be/IIX78qGYeAo

Infantile Spasm video: https://youtu.be/aVoJtslvqOU

Some images by Getty Images

References:
Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH): therapeutic decision-making in real-life cases. Clin Kidney J. 2013 Nov; 6(Suppl 1): i1–i20. https://https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438352/

Regulation of arginine vasopressin in the syndrome of inappropriate antidiuresis. Am J Med 2006; 119:S36. https://pubmed.ncbi.nlm.nih.gov/16843083/

Nausea and vasopressin. Lancet. 1991;337(8750):1133. https://pubmed.ncbi.nlm.nih.gov/1674020/

The syndrome of inappropriate antidiuretic hormone secretion of unknown origin. Am J Kidney Dis 1999; 33:161. https://pubmed.ncbi.nlm.nih.gov/9915284/

Pathophysiology and etiology of the syndrome of inappropriate antidiuretic hormone secretion (SIADH). UpToDate. https://www.uptodate.com/contents/pathophysiology-and-etiology-of-the-syndrome-of-inappropriate-antidiuretic-hormone-secretion-siadh