(1-10-2022) Update: Spike Protein Goes to Nucleus (Expression of Concern)

2 years ago
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(1-10-2022) Update: Spike Protein Goes to Nucleus (Expression of Concern)

The in-vitro study about the Spike protein going to the nucleus has an expression of concern (EOC). An investigation is ongoing. Let's review.

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URL list from Monday, Jan. 10 2022

Viruses | Free Full-Text | Expression of Concern: Jiang, H.; Mei, Y.-F. SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro. Viruses 2021, 13, 2056 | HTML
https://www.mdpi.com/1999-4915/14/1/12/htm#B1-viruses-14-00012

SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro - PMC
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8538446/

A 2011 study about the SARS-COV (not SARS-COV-2) in similar lines.
SARS-CoV 9b Protein Diffuses into Nucleus, Undergoes Active Crm1 Mediated Nucleocytoplasmic Export and Triggers Apoptosis When Retained in the Nucleus
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019436

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