One dose of COVID-19 vaccine may induce immunity in recovered patients

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A new analysis of antibody responses in 44 people, who received either the Pfizer or Moderna mRNA vaccines, shows that only one dose may be needed for previously infected patients who have since recovered. The study also supported that two doses are optimal to induce strong antibody and B cell responses in patients who are immunologically naïve for COVID-19, and antibodies induced by the vaccination could protect against the more infectious and deadly South African variant. The results build on an increasing body of research suggesting that people previously infected with COVID-19 may only require one dose of mRNA vaccination for optimal immune responses, including new correlations with COVID-19-specific immune responses in these patients.

References:
http://dx.doi.org/10.1126/sciimmunol.abi6950

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