5th messenger poured out his vial upon the seat of the beast and his kingdom became full of darkness

"And the fifth messenger poured out his vial upon the seat of the beast; and his kingdom became full of darkness; and they gnawed their tongues for pain, And blasphemed HaElohim (the God) of heaven because of their pains and their sores, and repented not of their deeds" Rev. 16:10-11
Note Rev 16:2 1st vial:
"And the first went, and poured out his vial upon the earth; and there fell a noisome and grievous sore upon the men which had the mark of the beast, and them which worshipped his image." Rev 16:2