Arizona Cardinals vs. Buffalo Bills: Prediction

That high floor should be on display in Week 1 as Buffalo contends with a box that is lacking playmakers for the Cardinals. Despite some minor changes, the expectations are that the Arizona run defense should struggle as much as they did last season where they finished 29th in yards per attempt against (4.7). The addition of Bilal Nichols in the trenches and Mack Wilson at linebacker should help in that regard, but how much? Nichols did have 23 run stops in 2023, but on 293 run snaps, a run stop rate of 7.85% is at best adequate for an interior defensive lineman. As for Mack Wilson, he’s a linebacker who has just 11 tackles for loss on 2,050 defensive snaps as a player who plays behind the line of scrimmage far too often. This shifts the focus back to Kyzir White who must play above his skill level if the Cardinals hope to contain, and slow down, the Bills' running backs this weekend.
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