If there's different strains of the virus, how does a vaccine work

Dr. Sabine Hazan: "Every family that we tested had the same virus strain. However, when you compare family in Atlanta to the family in Beverly Hills who had Covid, different strain of the virus. And right away I said to myself, if there's different strains of the virus, how does a vaccine work, even if a vaccine is the spike protein...
A vaccine, you have to match. If a sequence is ABC, your vaccine has to be ABC. If your sequence is AFG, AFG is the vaccine. Now the sequence changes from from ABC, but your vaccine is ABC and now you have AWX, ABC is not gonna work. It has to match to recognize the microbe, so that it create an immunity."