2006 Lions at Patriots

Though the Lions led for the majority of the contest, they were unable to hang on for a victory over the AFC East-leading New England Patriots. Detroit made plays on both sides of the ball, but ultimately it was turnovers down the stretch that gave the Patriots the edge and the 28-21 win. "We had our chance to win," Lions running back Kevin Jones said, "but at the end of the game, we gave it away."