How Magic Mushrooms Can Change Your Brain Forever

New research advances efforts to harness drug’s mind-altering power to treat mental illness.
A new study demonstrates that psilocybin, the active compound in magic mushrooms, affects the brain by temporarily altering critical introspective networks, which can lead to profound psychological transformations. These findings point towards potential uses of psilocybin in developing treatments for mental health disorders like depression.

People who consume psilocybin-containing mushrooms — otherwise known as magic mushrooms — typically undergo a surreal experience in which their sense of space, time, and self is distorted. Advocates have long argued that, under the right conditions, psychedelic experiences can alleviate mental distress, and a smattering of scientific studies suggests they may be right. Understanding precisely how the drug affects the brain will help scientists and doctors harness its therapeutic potential.