Largest Ever Obesity Study Showcases Semaglutide’s Promise

Two important studies stemming from the largest and most prolonged clinical trial of semaglutide’s impact on weight in more than 17,000 non-diabetic adults with overweight and obesity reveal that participants lost an average of 10% of their body weight and more than 7 centimeters from their waistline over four years.

Clinically meaningful weight loss was achieved by men and women of all races, ages, and body sizes, across all regions, with a lower rate of serious adverse events compared with placebo.

Over half of adults taking semaglutide moved down at least one BMI category after 2 years compared to 16% receiving placebo, and 12% reached a healthy BMI (25 kg/m² or less) compared with 1% in the placebo group.