Appetite and Energy Balance: The Hormone Connection | May 2, 2023

On Tuesday, May 2, 2023, Linda Bazinet explained the answer to Why Is This Mouse Fat? Control of appetite and energy balance is complex. However, the fat mouse has a simple problem—it is unable to synthesize he hormone Leptin. We will look a the history of leptin and it’s role in regulating our appetite and body weight. We will also look at ghrelin which in many ways is opposite to leptin. In fact, ghrelin is known as the “hunger hormone”. In addition, we will look at other hormones that are involved in appetite and energy balance including the digestive hormone cholecystokinin (CCK). The key role of the appetite center in the hypothalamus will also be discussed.

You Will Learn:
- Leptin suppresses appetite & increases energy expenditure.
- What is leptin resistance and can you change it?
- Ghrelin dramatically increases hunger but it also stimulates GH secretion.
- What causes abnormal ghrelin levels and can they be restored to normal?
- CCK not only regulates digestion but is also a satiety signal.

Linda Bazinet, BSc, MSc

Linda received her B.Sc. (Zoology) from the University of Toronto and then completed her M.Sc. (Cell Biology) at McMaster University. With over 30 years of teaching experience, Linda's passion as a science educator is to both inform and excite students about the natural world in general and the human body in particular. Linda has taught a wide variety of courses at both Seneca and Sheridan College including Biology, General and Inorganic Chemistry, Mathematics, Microbiology, Histology, Laboratory Techniques and Environmental Science. Linda currently teaches Biological Chemistry, Human Anatomy & Physiology, Body Metabolism and Endocrinology at The Institute of Holistic Nutrition.

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