Researchers Discover New Origin of Deep Brain Waves

Understanding hippocampal activity could improve sleep and cognition therapies.
Researchers from the University of California, Irvine’s biomedical engineering department have discovered a new origin for two essential brain waves—slow waves and sleep spindles—that are critical for deep sleep. While it was traditionally thought that these brain waves originated solely from a circuit connecting the thalamus and cortex, the team’s findings, published in Scientific Reports, suggest that the axons in memory centers of the hippocampus play a role.

For decades, slow waves and sleep spindles have been identified as essential elements of deep sleep, measured through electroencephalography recordings on the scalp. However, the UC Irvine-led team revealed a novel source of these brain waves within the hippocampus and were able to measure them in single axons.