Premium Only Content
A New Tool for Men’s Testosterone & Fertility: Opioid Antagonists
👉🏻 Ways to support and save (affiliate links):
- LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO
- Nurosym: https://nurosym.com Discount Code: LucieC5
-CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE
- Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh
🔗 Connect & Explore 🔗
JOIN THE COMMUNITY:
Reddit ▶ The Long-Lived Community / thelonglived
Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh
TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1
GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/
OTHER CHANNELS
Lucie ▶ / @luciec.7692
Kids ▶ / @bilinguini
🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7
🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.
Citations:
Bouret, S., Prevot, V., Croix, D., Viltart, O., Stefano, G. B., Mitchell, V., & Beauvillain, J. C. (2000). μ Opioid receptor mRNA expression in neuronal nitric oxide synthase-immunopositive preoptic area neurons. Molecular brain research, 80(1), 46-52. https://www.sciencedirect.com/science/article/abs/pii/S0169328X00001182
Petraglia, F., Vale, W., & Rivier, C. (1986). BETA-ENDORPHIN MODULATES THE INHIBITORY ACTION OF CORTICOTROPIN-RELEASING FACTOR ON LUTEINIZINC HORMONE SECRETION. Progress in Opioid Research, 331. https://books.google.com/books?hl=en&lr=&id=1KqJllN9ghQC&oi=fnd&pg=PA331&dq=Petraglia,+F.,+Value,+WITH.,+%26+Rivier,+C.+(1986).+BETA-ENDORPHIN+MODULATES+THE+INHIBITORY+ACTION+OF+CORTICOTROPIN-RELEASING+FACTOR+ON+LUTEINIZING+HORMONE+SECRETION.%C2%A0Progress+in+Opioid+Research,+331.&ots=Bd2uV04s8C&sig=_0-5K5a_H702kOm0bWK0QBYJTkM#v=onepage&q&f=false
Wiesner JB, Koenig JI, Krulich L, Moss RL 1984 Site of action for -endorphin-induced changes in plasma luteinizing hormone and prolactin in the ovariectomized rat
https://www.sciencedirect.com/science/article/abs/pii/0024320584900614
Pimpinelli, F., Parenti, M., Guzzi, F., Piva, F., Hokfelt, T., & Maggi, R. (2006). Presence of delta opioid receptors on a subset of hypothalamic gonadotropin releasing hormone (GnRH) neurons. Brain research, 1070(1), 15-23. https://www.sciencedirect.com/science/article/abs/pii/S0006899305015453
Weems, P. W., Coolen, L. M., Hileman, S. M., Hardy, S., McCosh, R. B., Goodman, R. L., & Lehman, M. N. (2018). Evidence that dynorphin acts upon KNDy and GnRH neurons during GnRH pulse termination in the ewe. Endocrinology, 159(9), 3187-3199. https://academic.oup.com/endo/article-abstract/159/9/3187/5053743
MOSTARI, M. P., Ieda, N., Deura, C., Minabe, S., Yamada, S., Uenoyama, Y., ... & Tsukamura, H. (2013). Dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats. Journal of Reproduction and Development, 59(3), 266-272. https://www.jstage.jst.go.jp/article/jrd/59/3/59_2012-193/_article/-char/ja/
Agirregoitia, E., Valdivia, A., Carracedo, A., Casis, L., Gil, J., Subiran, N., ... & Irazusta, J. (2006). Expression and localization of δ-, κ-, and μ-opioid receptors in human spermatozoa and implications for sperm motility. The Journal of Clinical Endocrinology & Metabolism, 91(12), 4969-4975.https://academic.oup.com/jcem/article-abstract/91/12/4969/2656533
Tenhola, H., Sinclair, D., Alho, H., & Lahti, T. (2012). Effect of opioid antagonists on sex hormone secretion. Journal of endocrinological investigation, 35(2), 227-230. https://link.springer.com/article/10.3275/8181
Li, X. F., Knox, A. M. I., & O'byrne, K. T. (2010). Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female. Brain research, 1364, 153-163. https://www.sciencedirect.com/science/article/abs/pii/S0006899310018184
Veldhuis, J. D., Rogol, A. D., Samojlik, E., & Ertel, N. H. (1984). Role of endogenous opiates in the expression of negative feedback actions of androgen and estrogen on pulsatile properties of luteinizing hormone secretion in man. The Journal of clinical investigation, 74(1), 47-55. https://www.jci.org/articles/view/111417
Jayaram-Lindström, N., Hammarberg, A., Beck, O., & Franck, J. (2008). Naltrexone for the treatment of amphetamine dependence: a randomized, placebo-controlled trial. American Journal of Psychiatry, 165(11), 1442-1448. https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2008.08020304
#pct #fertility #testosterone
-
2:24
Leo & Longevity
9 months agoRoger Stone on Miscarriages of Justice (e.g. the McCloskeys)
87 -
1:42:38
Tucker Carlson
2 days agoOliver Stone & Peter Kuznick: War Profiteering, Nuclear Tech, NATO v. Russia, & War With Iran
143K327 -
3:29
IyahMay
1 day ago $3.17 earnedIyah May - Karmageddon (Lyric Music Video)
12.9K41 -
1:34:20
Roseanne Barr
1 day ago $20.64 earnedIt's a Vibe with Berry Gordy IV | The Roseanne Barr Podcast #82
58.6K117 -
32:37
Anthony Pompliano
2 days ago $3.32 earnedWill Amazon & Microsoft Buy Bitcoin?!
28.1K4 -
17:40
VSiNLive
1 day agoHow a TWEET Made Steve Fezzik DOUBLE DOWN on this Vikings Rams Bet Amidst the California Wildfires
30.8K3 -
22:20
DeVory Darkins
17 hours ago $7.75 earnedGavin Newsom Suffers HUMILIATING Blow by Trump
25.9K58 -
24:15
Stephen Gardner
21 hours ago🚨New Evidence DESTROYS Gavin Newsom! Trump HITS BACK HARD!!
34.3K258 -
14:59
TimcastIRL
4 hours agoH1-B Immigration ABUSED, You Cannot Import Your Way Out Of US Cultural Decay
35.9K27 -
15:21
Forrest Galante
17 hours agoWorld's Deadliest Predator Up Close (Private Tour)
35.2K4