A New Tool for Men’s Testosterone & Fertility: Opioid Antagonists

8 months ago
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Citations:
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Petraglia, F., Vale, W., & Rivier, C. (1986). BETA-ENDORPHIN MODULATES THE INHIBITORY ACTION OF CORTICOTROPIN-RELEASING FACTOR ON LUTEINIZINC HORMONE SECRETION. Progress in Opioid Research, 331. https://books.google.com/books?hl=en&lr=&id=1KqJllN9ghQC&oi=fnd&pg=PA331&dq=Petraglia,+F.,+Value,+WITH.,+%26+Rivier,+C.+(1986).+BETA-ENDORPHIN+MODULATES+THE+INHIBITORY+ACTION+OF+CORTICOTROPIN-RELEASING+FACTOR+ON+LUTEINIZING+HORMONE+SECRETION.%C2%A0Progress+in+Opioid+Research,+331.&ots=Bd2uV04s8C&sig=_0-5K5a_H702kOm0bWK0QBYJTkM#v=onepage&q&f=false

Wiesner JB, Koenig JI, Krulich L, Moss RL 1984 Site of action for -endorphin-induced changes in plasma luteinizing hormone and prolactin in the ovariectomized rat
https://www.sciencedirect.com/science/article/abs/pii/0024320584900614

Pimpinelli, F., Parenti, M., Guzzi, F., Piva, F., Hokfelt, T., & Maggi, R. (2006). Presence of delta opioid receptors on a subset of hypothalamic gonadotropin releasing hormone (GnRH) neurons. Brain research, 1070(1), 15-23. https://www.sciencedirect.com/science/article/abs/pii/S0006899305015453

Weems, P. W., Coolen, L. M., Hileman, S. M., Hardy, S., McCosh, R. B., Goodman, R. L., & Lehman, M. N. (2018). Evidence that dynorphin acts upon KNDy and GnRH neurons during GnRH pulse termination in the ewe. Endocrinology, 159(9), 3187-3199. https://academic.oup.com/endo/article-abstract/159/9/3187/5053743

MOSTARI, M. P., Ieda, N., Deura, C., Minabe, S., Yamada, S., Uenoyama, Y., ... & Tsukamura, H. (2013). Dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats. Journal of Reproduction and Development, 59(3), 266-272. https://www.jstage.jst.go.jp/article/jrd/59/3/59_2012-193/_article/-char/ja/

Agirregoitia, E., Valdivia, A., Carracedo, A., Casis, L., Gil, J., Subiran, N., ... & Irazusta, J. (2006). Expression and localization of δ-, κ-, and μ-opioid receptors in human spermatozoa and implications for sperm motility. The Journal of Clinical Endocrinology & Metabolism, 91(12), 4969-4975.https://academic.oup.com/jcem/article-abstract/91/12/4969/2656533

Tenhola, H., Sinclair, D., Alho, H., & Lahti, T. (2012). Effect of opioid antagonists on sex hormone secretion. Journal of endocrinological investigation, 35(2), 227-230. https://link.springer.com/article/10.3275/8181

Li, X. F., Knox, A. M. I., & O'byrne, K. T. (2010). Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female. Brain research, 1364, 153-163. https://www.sciencedirect.com/science/article/abs/pii/S0006899310018184

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#pct #fertility #testosterone

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