Propanolol Makes Amphetamine More Bioavailable + Mother's Testosterone = Offspring Aggression + More

Citations:
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Bernardo, A., Plumitallo, C., De Nuccio, C., Visentin, S., & Minghetti, L. (2021). Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ. Scientific reports, 11(1), 1-13.
https://www.nature.com/articles/s41598-021-83938-y
Bentz, A. B., Niederhuth, C. E., Carruth, L. L., & Navara, K. J. (2021). Prenatal testosterone triggers long-term behavioral changes in male zebra finches: unravelling the neurogenomic mechanisms. BMC Genomics, 22(1), 1-11. https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-021-07466-9
Hrtanek, I., Bittsansky, M., Tonhajzerova, I., Grendar, M., Oppa, M., Cesnekova, D., ... & Ondrejka, I. (2021). The impact of external stress factors on hippocampus volume during antidepressant treatment. The European Journal of Psychiatry. https://www.sciencedirect.com/science/article/abs/pii/S0213616320301129
Wu, K. C., Haberlen, S. A., Plankey, M. W., Palella, F. J., Piggott, D. A., Kirk, G. D., ... & Post, W. S. (2021). Human immunodeficiency viral infection and differences in interstitial ventricular fibrosis and left atrial size. European Heart Journal-Cardiovascular Imaging. https://www.x-mol.com/paper/1368821985431937024
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TIMESTAMPS (thanks to the MVS Jax)
0:00 Intro
0:51 Stimulants and ADHD
1:20 5 hydroxy derivatives of amphetamine and methamphetamine and CYP2D6
2:55 Low doses of amphetamines
4:06 Amphetamines vs methamphetamine
5:03 Ritalin
6:11 Propranolol and CYP2D6
8:00 Propranolol and amphetamines
9:20 Curcumin, Myelin, and the PPAR gamma receptor
10:40 Progesterone signaling/ TRT
11:20 Androgenicity of mothers and behavior of their offspring
12:50 Hippocampal volume and life stress
14:34 HIV and CART
15:02 Inflammation and coronary stenosis
15:44 MIF
16:07 Adding fiber to a high fat diet
17:16 Non alcoholic fatty liver disease, hepatic steatosis, and ulcerative colitis
18:52 SSRIs, suicide risk, and new age antidepressants.

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