Mechanisms of GLP-1
10 months ago
37
After activation by full agonists such as GLP-1,GLP-1R(1)couples with Gas activates adenolate cyclase(AC),and causes the accumulation of cAMP.With increasing cAMP levels, protein kinase A(PKA) and the exchange protein directly activated by cAMP-2(Epac-2) are also activated. PKA and Epac-2 trigger the closure of KATP and KV channels,which depolarizes the cell membrane opens voltage-dependent Calcium channels(VDCC) and causes Calcium influx and the promotion of insulin secretion by the islet beta cells. https://www.medicilon.com/videos/mechanisms-of-glp-1/
Loading comments...
-
LIVE
Akademiks
2 hours agoYo Gotti Brother put a 100K hit on Young Dolph. 1 Shooter is SNTICHING on Everything! Diddy Update
4,270 watching -
1:20:30
Lee Camp
5 hours agoLIVE: Israel Collapse Coming / Wage Theft Shocking / Former CIA Head Admits Truth
21.1K -
20:49
Freakin' Reviews
1 day agoTesting and Ranking 5 Gadgets Under $20!
13.2K4 -
7:48
Fore Play Golf
1 day agoWill the PGA Tour-PIF Deal EVER Happen?
28.5K7 -
28:04
The Black and Jewish Podcast with Ashira Solomon
2 months agoEp. 1: Black People and Jewish People
30.2K32 -
2:00:28
Revenge of the Cis
4 hours agoEpisode 1379: Danger
25.6K4 -
1:05:26
In The Litter Box w/ Jewels & Catturd
21 hours agoRINO Republicans Lack Resolve | In the Litter Box w/ Jewels & Catturd – Ep. 652 – 9/23/2024
46.2K17 -
2:10:11
Barstool Yak
7 hours agoThe Yak with Big Cat & Co. Presented by Rhoback | The Yak 9-23-24
26.4K5 -
1:33:59
The Quartering
6 hours agoKamala Harris Panics As Old Clip Resurfaces, DOJ Places Public Bounty On Donald Trump & More
65.9K54 -
23:47
Stephen Gardner
4 hours ago🔴IT'S OVER! CONGRESS CAN'T HIDE THIS NOW | TRUMP'S LIFE IN DANGER!
35.1K63