Buffalo Bills vs Jacksonville Jaguars Prediction and Picks - NFL Picks Week 5

If you are looking for NFL football picks and predictions for the Week 5 NFL matchup between the Buffalo Bills and Jacksonville Jaguars, we have you covered! Our NFL football handicapping experts discuss the opening weekend from a sports betting perspective, sharing their picks and predictions vs. the current odds.

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Buffalo Bills vs. Jacksonville Jaguars Betting Preview Week 5

Date: October 8, 2023

Time: 9:30am ET

Location: Tottenham Hotspur Stadium in London, England

Watch on TV: Tune in to NFL Network for live coverage.

Twitter Hashtags: #BuffaloBills #JacksonvilleJaguars

Current Spread and Total: Bills -5.5 with a total of 48.

Interesting Facts: The Buffalo Bills are known for their passionate fan base, known as the "Bills Mafia," and have been a strong contender in recent NFL seasons. The Jacksonville Jaguars are a team in transition, with a young roster and high hopes for the future.

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