The EXCITING WORLD of CANNABINOID METABOLITES

References:

CBD vs THC: The Difference Explained | by Aaron Cadena - Medium. https://medium.com/cbd-origin/cbd-vs-thc-the-difference-explained-b3cfc1da52f0.
Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes .... https://dmd.aspetjournals.org/content/dmd/49/12/1070.full.pdf.
The Entourage Effect: How THC and Other Weed Compounds Mix - WIRED. https://www.wired.com/story/cannabis-science-entourage-effect/.
Pharmacology and effects of cannabis: A brief review. https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/pharmacology-and-effects-of-cannabis-a-brief-review/82B02735F420CB287DCC80843FC34AE1.
undefined. https://doi.org/10.1192/bjp.178.2.101.
Cannabinoids and Pain: New Insights From Old Molecules. https://www.frontiersin.org/articles/10.3389/fphar.2018.01259/full.
Cannabinol - Wikipedia. https://en.wikipedia.org/wiki/Cannabinol.
Frontiers | Cannabidiol as a Therapeutic Target: Evidence of its .... https://www.frontiersin.org/articles/10.3389/fphar.2020.595635/full.
11-Hydroxy-THC - Wikipedia. https://en.wikipedia.org/wiki/11-Hydroxy-THC.
Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes .... https://dmd.aspetjournals.org/content/49/12/1070.
CBD vs. THC: A Chart to Help You Understand Cannabis - Verywell Health. https://www.verywellhealth.com/cbd-vs-thc-5272060.
11-Hydroxyhexahydrocannabinol - Wikipedia. https://en.wikipedia.org/wiki/11-Hydroxyhexahydrocannabinol.
A study titled “Cannabinomics: Application of Metabolomics in Cannabis” discusses the application of metabolomics in cannabis research and development1. The study focuses on the psychoactive cannabinoid tetrahydrocannabinol (Δ 9 -THC) and the non-psychoactive cannabidiol (CBD), which are the two major cannabinoids that have monopolized the research interest1.
Another study titled “The biosynthesis of the cannabinoids” surveys the biosynthesis and biochemistry of cannabinoids2. The pathways and the enzymes’ mechanisms of action are discussed as is the non-enzymatic decarboxylation of the cannabinoic acids2.
A study titled “Variation in Cannabinoid Metabolites Present in the Urine of Adults Using Medical Cannabis Products in Massachusetts” examines the association between medical cannabis product use and exposure to THC and CBD3. The study quantified levels of THC, CBD, and their metabolites in urine of participants in a clinical trial3.
A study titled “Metabolites of Cannabis Induce Cardiac Toxicity and …” indicates that the major metabolites of cannabis, THC-OH and THC-COOH induce morphological changes in the cytoskeleton, hypermotility coupled with increased wound healing and ECM deposition4.
11-Hydroxy-THC - Wikipedia. https://en.wikipedia.org/wiki/11-Hydroxy-THC.
What Is 11-hydroxy-THC? Understanding the THC Metabolite - Leafwell. https://leafwell.com/blog/11-hydroxy-thc/.
What Is 11-hydroxy-THC? 11-hydroxy-THC Definition | Weedmaps. https://weedmaps.com/learn/dictionary/11-hydroxy-thc.