Dr. Tour DISSECTS Chemistry of an ‘Expert’ on OoL - Lee Cronin, Part 02, debunking Professor Dave

*THIS is Episode 2* - _Dissecting Lee Cronin’s Origin of Life Chemistry - Lee Cronin, Part 02_
Ep 1: https://youtu.be/4rwPi1miWu4
Ep 3: https://youtu.be/v3A8_ezYlZY
Ep 4: https://youtu.be/N_on6LK6Etc
Ep 5: https://youtu.be/t5PfBzQUjW8
Ep 6: https://youtu.be/ZtitTE2BavU
Ep 7: https://youtu.be/cL0NIFk1grE
Ep 8: https://youtu.be/atxmIZw3DdA
*Episode 9 premieres soon! SUBSCRIBE so you'll be notified!*

In this episode, we continue with Lee Cronin and turn to his chemistry. Facing accusations of being nefarious and of misquoting terms with an intent to mislead, Dr. James Tour corrects the record and shows how Cronin’s own statements ultimately mislead laypersons to falsely believe that today’s scientists can create life. With Cronin stating awareness of life’s vast requirements, Dr. Tour reminds us that Cronin’s autocatalytic experiments have not generated anything that resembles or moves towards satisfying those requirements. Dr. Tour then digs into published literature by Cronin and exposes how the experimentals lack prebiotic relevance, including a massive yield of products, intentional human removal, and the inability to use the vast array of isomers. Peptides in water (really in dry state), sterilization temperature requirements, and unprotected side chains — all such things lead to speculation if these are used in an abiogenesis narrative, agrees a peptide chemical expert.

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Check out all our episodes:
*Addressing Abiogenesis, Season 2*
https://youtube.com/playlist?list=PLILWudw_84t22BWvWsoXCmaXNllbfJ2h7

*Addressing Abiogenesis, Season 1*
https://youtube.com/playlist?list=PLILWudw_84t2THBvJZFyuLA0qvxwrIBDr

VIDEO INDEX
00:00 University of Glasgow
00:55 Previously, Lee Cronin Part 01
02:19 Nefarious
04:02 Real Life from Scratch
04:57 Public Perception
06:07 Drugs and Robots
06:57 Characteristics of Life
07:48 Autocatalysis
11:39 Crude Requirements for Life
11:55 Invoking a Creator
12:41 Biased Perhaps?
14:36 Cannizzaro and Formose Reactions
17:01 Reading Papers
17:58 Calcium Hydroxide
19:57 There are Billions
21:30 Less of a Mess?
23:50 So Many Isomers
25:25 Peptide Wet/Dry Cycles
28:12 Peptides in Water
29:22 Peptide Bonds
29:59 Peptides and Proteins: A Closer Look
31:07 Dipeptides
33:15 Sterilization Temperatures
36:22 Checking Lee Cronin’s Work
38:20 A Bunch of Junk
38:43 Next Time: Addressing Lee Cronin Part 03

#abiogenesis #originoflife #evolution

Papers addressed in Cronin series:
- Spontaneous formation of autocatalytic sets with self-replicating inorganic metal oxide clusters; https://www.pnas.org/doi/full/10.1073/pnas.1921536117
- Autocatalysis: Kinetics, Mechanisms and Design; https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/syst.202000026
- Taming the Combinatorial Explosion of the Formose Reaction via Recursion within Mineral Environments; https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/syst.201900014
- Formation of oligopeptides in high yield under simple programmable conditions; https://www.nature.com/articles/ncomms9385
- Amino Acid Structures; https://www.neb.com/tools-and-resources/usage-guidelines/amino-acid-structures
- Autonomous model protocell division driven by molecular replication; https://www.nature.com/articles/s41467-017-00177-4

God bless.

~
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