Bret and Heather 188th DarkHorse Podcast Livestream: Play the Hand You Are Dealt

In this 188th in a series of live discussions with Bret Weinstein and Heather Heying (both PhDs in Biology), we discuss the state of the world through an evolutionary lens.

In this episode we discuss medicine, scientific publishing, and just how bad things have gotten. The New England Journal of Medicine declined to publish a letter that would have provided valuable scientific context for a paper they recently published, and we discuss Bret’s reserve capacity hypothesis regarding the evolution of senescence and the relationship of telomere length to both aging and cancer. Then we discuss uterine transplants. What can be done for women who are born without uteruses who want to bear children of their own? What about for men who present themselves to the world as women? How about women who have transitioned “into” men but have decided that they would like to bear children after all? And who can get Continuing Medical Education credits from the American Medical Association for pretending that up is down, male is female, and reality is a thing of the past? You can!

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Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://a.co/d/dunx3at

Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org

Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com

Find more from us on Bret’s website (https://bretweinstein.net) or Heather’s website (http://heatherheying.com).

Become a member of the DarkHorse LiveStreams, and get access to an additional Q&A livestream every month. Join at Heather's Patreon.

Like this content? Subscribe to the channel, like this video, follow us on twitter (@BretWeinstein, @HeatherEHeying), and consider helping us out by contributing to either of our Patreons or Bret’s Paypal.

Looking for clips from #DarkHorseLivestreams? Check out our other channel: https://www.youtube.com/channel/UCAWCKUrmvK5F_ynBY_CMlIA

Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music.

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Q&A Link: https://rumble.com/v3avyq9-your-questions-answered-bret-and-heather-188th-darkhorse-podcast-livestream.html

Mentioned in this episode:

DeBoy et al 2023. Familial Clonal Hematopoiesis in a Long Telomere Syndrome. New England Journal of Medicine. https://www.nejm.org/doi/full/10.1056/NEJMoa2300503

DarkHorse Livestream #172 (“20 Years Later”): https://www.youtube.com/live/CcgzrMrnBUE

Weinstein & Ciszek 2002. The reserve-capacity hypothesis: evolutionary origins and modern implications of the trade-off between tumor-suppression and tissue-repair. Experimental gerontology, 37(5): 615-627.http://176.9.41.242/doc/longevity/2002-weinstein.pdf

Castellón et al 2017. The history behind successful uterine transplantation in humans. JBRA assisted reproduction, 21(2): 126: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473706/pdf/jbra-21-02-0126.pdf

Murphy & Mumford 2023. Should Uterus Transplantation for Transwomen and Transmen Be Subsidized? AMA Journal of Ethics, 25(6): 431-436. https://journalofethics.ama-assn.org/article/should-uterus-transplantation-transwomen-and-transmen-be-subsidized/2023-06

Continuing Medical Education credits through the AMA: https://www.ama-assn.org/education/ama-pra-credit-system

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Timestamps:
(00:00) Wait
(06:20) Welcome
(11:20) Sponsors
(19:40) Senescence, telomeres, and NEJM background
(46:40) Bret's contribution
(01:01:03) Uterine transplants
(01:32:05) Medical quiz
(01:44:20) Wrap up