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Autopsy Proven Fatal COVID-19 Vaccine-Induced Myocarditis
Dr. John Campbell
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Autopsy Proven Fatal COVID-19 Vaccine-Induced Myocarditis
https://www.preprints.org/manuscript/...
COVID-19 vaccines have been linked to myocarditis which in some circumstances can be fatal.
This systematic review aims to investigate potential causal links between COVID-19 vaccines and death from myocarditis using post-mortem analysis.
A systematic review of all published autopsy reports involving COVID-19 vaccination-related myocarditis
Through July 3rd, 2023.
All autopsy studies that include COVID-19 vaccine-induced myocarditis as a possible cause of death were included
Causality in each case
Determined by three independent reviewers with cardiac pathology experience and expertise.
Results
Initially identified 1,691 studies
After screening, 14 papers, 28 autopsy cases.
(The cardiovascular system was the only organ system affected in 26 cases)
In 2 cases, myocarditis a consequence from multisystem inflammatory syndrome (MIS).
Number of days from last COVID-19 vaccination until death
We established that all 28 deaths were causally linked to COVID-19 vaccination by independent adjudication.
Conclusions
Temporal relationship, internal and external consistency
Deceased, with known COVID-19 vaccine-induced myocarditis
Pathobiological mechanisms
Related excess death
Complemented with autopsy confirmation
Independent adjudication
Application of the Bradford Hill criteria
Overall epidemiology of vaccine myocarditis
suggests there is a high likelihood of a causal link between COVID-19 vaccines and death from suspected myocarditis,
in cases where sudden, unexpected death has occurred in a vaccinated person.
Urgent investigation is required for the purpose of risk stratification, and mitigation,
in order to reduce the population occurrence of fatal COVID-19 vaccine-induced myocarditis.
More information
Most cases had symptoms consistent with myocarditis prior to death, (chest pain, effort intolerance)
Choi et al, a 22-year-old Korean man
Autopsy showed intense inflammation and destruction of cardiac tissue including the conduction system.
Other cases had no reported symptoms before death.
Gill et al reported two boys, age 16 and 17, who died a few days after mRNA injection while asleep at home.
Autopsies revealed patchy inflammation suggesting that sudden arrhythmic death had occurred.
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