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Latest Research: Why Deep Sleep is NOT the MOST IMPORTANT!
A new study out of the University of Oslo has changed the perception as to which stage of sleep is best for clearing the brain of waste products as we sleep.
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The word "brainwashing" usually triggers negative associations. But our continued brain health depends on this vital process. Scientists at the University of Oslo recently made new and important discoveries about how and why this cleaning happens when we are sleeping. The blood vessels in the brain constrict and dilate in certain patterns while we sleep, and this is one of the key mechanisms that drives the clearance of harmful waste products from our brain.
Rune Enger, the last author of this latest study, and an Associate Professor from the Letten Centre at the University of Oslo said "Our discoveries can help us find new ways to treat or even prevent Alzheimer's disease and other neurodegenerative diseases. These findings can also help to create strategies to deliver drugs to the brain more efficiently."
"Brainwashing" or “brain waste clearance” is a process of removing harmful waste products from the brain. The brain, as it works throughout the day, continually producing waste matter, these materials include proteins called Beta-amyloid and Tau, and if too many of them accumulate, it raises the risk of Alzheimer's disease and other age-related neurodegenerative diseases.
The blood vessels in our brain dilate and constrict in specific patterns as we sleep. Waste products from the brain are cleared along specialized tunnels around the brain blood vessels. This movement of the blood vessels could affect this process. The researchers examined what was going on in the brains of sleeping mice using an advanced laser microscope.
They discovered that the blood vessels in the brain, specifically the arteries, dilated and constricted in certain patterns while the mice were sleeping. These movements were not observed in mice that were awake.
Until now, it was believed that it was only deep sleep that was involved in this cleansing of waste products. However, in this study, the researchers observed something striking. The blood vessels in the brain constricted and dilated in patterns unique to each sleep stage of the entire sleep cycle, including deep sleep, REM sleep and even the brief awakenings that pepper our nightly sleep, and are a natural part of our sleep cycle.
During deep sleep the arteries slowly dilated and constricted, but as the transition to REM sleep occurred, these became smaller while the artery slowly dilated. During REM sleep arteries stayed dilated before quickly constricting at the end of a sleep cycle to the same size as before falling asleep. the constrictions also happen during the brief awakenings experienced during sleep.
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