PCOS Quick Facts

In women with PCOS, insulin resistance is thought to play a key role in the development of the condition. Insulin resistance can cause the ovaries to produce more androgens, which are male hormones that can interfere with ovulation and lead to other PCOS symptoms like irregular periods and acne. High insulin levels can also lead to increased production of insulin-like growth factor-1 (IGF-1), which can stimulate the ovaries to produce more androgens.

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