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New Research: EATING at WHAT TIME of Day Aids in WEIGHT LOSS & Longevity?
a new study out of the Brigham and Women’s Hospital in Boston has shown that the later in the day you eat has a profound effect on the hormones that control your appetite and on your circadian rhythm.
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Links:
https://pubmed.ncbi.nlm.nih.gov/36198293/
https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(22)00397-7
https://europepmc.org/article/med/36198293
https://plu.mx/plum/a/?doi=10.1016/j.cmet.2022.09.007
https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(22)00344-8
https://www.pnas.org/doi/full/10.1073/pnas.1008734107
https://onlinelibrary.wiley.com/doi/full/10.1111/jne.12886
https://pubmed.ncbi.nlm.nih.gov/28975706/
Until now, very few studies have actually investigated precisely why late-night eating is linked to greater body weight. This recent study set out to add to this deficit. Researchers found that eating four hours later than normal actually changed many of the physiological and molecular mechanisms in our body that in turn promote weight gain. This work adds to other recently published work which has found that eating earlier in the day is more beneficial for both appetite and weight contrOL.
To conduct their study, the researchers had 16 participants follow two different meal schedules, each for a period of six days in total. The first protocol had participants eat their meals early in the day with the last meal consumed approximately six hours and 40 minutes before bedtime. So, for a bedtime of 10pm, that would mean not eating after 3.20 in the afternoon. The second protocol had participants eat all of their daily meals approximately four hours later. So for a 10pm bed time, that would mean not eating after 7.20 in the evening.
The study was conducted in a controlled lab environment.
This ensured that the participants in each group consumed an identical diet; all of their meals were evenly spaced, with around four hours between each sitting. To understand how late eating affected the body, the researchers specifically looked at three different measures which are associated with weight gain:
o The influence of appetite
o The impact of eating time on energy expenditure (calories burned), and
o Molecular changes from fat tissue.
The participants’ appetite was measured throughout using two techniques. The first technique, a more subject method, had the participants rate their feelings of hunger throughout the day. The second technique was collecting blood samples to look at the levels of appetite-regulating hormones in participants' blood. These hormones were leptin (which helps us feel full) and ghrelin (which makes us feel hungry). These hormones were assessed hourly, over a 24 hour period, during the third and sixth day of each trial.
To assess the effect of meal timing on daily energy expenditure, a technique called "indirect calorimetry" was used. This measures both the amount of oxygen a person uses alongside the amount of carbon dioxide they produce. This helps researchers estimate how many calories a person's body uses throughout a normal day.
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