mRNA/mDNA 'εμβόλια' και αλλαγή του ανθρώπινου γονιδιώματος -νέο συνθετικό είδος transhuman 2.0.

REFERENCES:
[1] Aldén M., Olofsson Falla F., Yang D., Barghouth M., Luan C.,Rasmussen M., De Marinis, Y. Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line. Curr. Issues Mol. Biol. 2022, Vol.44, pp.1115-1126.
[2] Ebeling M, Küng E, See A, Broger C, Steiner G, Berrera M, Heckel T, Iniguez L, Albert T, Schmucki R, Biller H, Singer T, Certa U. Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment.
Genome Res. 2011, Vol.21, No.10, pp.1746-56.
[3] Fong V., Penn State, Eberly College of Science. Analysis of Rhesus Monkey Genome Uncovers Diferences
with Humans, Chimps (17th April 2007). [Online] 30 June 22. Avail. at:https://science.psu.edu/news/analysis-rhesus-monkey-genome-uncovers-differences-humans-chimps

[4] Graves J., The Conversation. Differences between men and women are more than the sum of their genes (30 July 2015).
[Online] 30 June 22. Avail. at: https://theconversation.com/differences-between-men-and-women-are-more-than-the-sum-of-their-genes-39490

[5] Felsenfeld G., A brief history of epigenetics. Cold Spring Harb Perspect Biol. 2014, Vol.6, No.1.
[6] Wanjek C., The NIH Catalyst (Intramural Research). Systems Biology as Defined by NIH: An Intellectual Resource for Integrative Biology (Vol.19, Issue 6, November-December 2011).[Online] 30 June 22. Avail. at:https://irp.nih.gov/catalyst/v19i6/systems-biology-as-defined-by-nih#:~:text=Systems%20biology%20is%20an%20approach,involves%20taking%20the%20pieces%20apart
.
[7] Navlakha S, Bar-Joseph Z. Algorithms in nature: the convergence of systems biology and computational thinking.
Mol Syst Biol. 2011, Vol.7, pp.546.
[8] Khalil R., El-Kordy A., Sobh H., Nature-Inspired Algorithms as a Part of the Biomimetic Architecture: A Brief Discussion.
Int Journal of Sciences: Basic and Applied Research (IJSBAR), 2022, Vol.62, No.1, pp.281-287.
[9] Moreno E. Design and construction of "synthetic species". PLoS One. 2012, Vol.7, No.7.
[10] Vidyasagar A., Live Science. Lanese N., What is CRISPR? (21 Oct 2021). [Online] 30 June 22. Avail. at: https://www.livescience.com/58790-crispr-explained.html

[11] Pak E., Harvard Medical School. CRISPR: A game-changing genetic engineering technique (31st July 2014).
[Online] 30 June 22. Avail. at: https://sitn.hms.harvard.edu/flash/2014/crispr-a-game-changing-genetic-engineering-technique/

[12] Marchese D., The New York Times. Talk. Her Discovery Changed the World. How Does She Think We Should Use It? (12 Aug 2022).[Online] 1st Aug 22. Avail. at: https://www.nytimes.com/interactive/2022/08/15/magazine/jennifer-doudna-crispr-interview.html

[13] Liu H., Wang K., Tang H., Gong Q., Du L., Pei X., Ye X. CRISPR/Cas9 editing of wheat TaQ genes alters spike morphogenesis and grain threshability. Journal of Genetics and Genomics, Vol.47, Issue 9, 2020, pp.563-575.
[14] Reardon S., Step aside CRISPR, RNA editing is taking off. Nature, Vol.578, 2020, pp.24-27.
[15] Marson A., Innovative Genomics Institute. CRISPR-based enhancers of DNA vaccines for COVID-19.
[Online] 30 June 22. Avail. at: https://innovativegenomics.org/projects/crispr-based-dna-vaccine-enhancer-covid-19/

[16] Ducharme J., TIME. mRNA's next chapter has nothing to do with COVID-19 vaccines (2nd Aug 2021).
[Online] 30 June 22. Avail. at: https://time.com/6080127/crispr-mrna/

[17] Isaacson W., TIME. mRNA technology gave us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry (11th Jan 2021). [Online] 30 June 22. Avail. at: https://time.com/5927342/mrna-covid-vaccine/

[18] Service R. F., Science. Forget single genes: CRISPR now cuts and splices whole chromosomes (29 Aug 2019).
[Online] 30 June 22. Avail. at: https://www.science.org/content/article/forget-single-genes-crispr-now-cuts-and-splices-whole-chromosomes

[19] Teufel M., Klein C.A., Mager M., Sobetzko P. A multifunctional system for genome editing and large-scale interspecies gene transfer. Nat Commun, Vol.13, 2022, pp.3430.
[20] Teague BP, Guye P, Weiss R. Synthetic Morphogenesis. Cold Spring Harb Perspect Biol. Vol.8, No.9, 2016.
[21] Regalado A., MIT Technology Review, Biotechnology. CRISPR creates new species with single giant chromosome (1st Aug 2018). [Online] 30 June 22. Avail. at: https://www.technologyreview.com/2018/08/01/2439/crispr-creates-new-species-with-single-giant-chromosome/

[22] Aguilera M., UC San Diego News Center. Synthetic SPECIES Developed for Use as a Confinable Gene Drive (2nd June 2021). [Online] 30 June 22. Avail. at:https://ucsdnews.ucsd.edu/pressrelease/synthetic-species-developed-for-use-as-a-confinable-gene-drive

[23] Cyranoski D., Nature. The CRISPR-baby scandal: what’s next for human gene-editing (11th March 2019).
[Online] 30 June 22. Avail. at:https://www.nature.com/articles/d41586-019-00673-1

[24] Hendry A. P., Gotanda K. M. and Svensson E. I. Human influences on evolution, and the ecological and societal consequences. Phil. Trans. R. Soc. B, 2017, pp.372.
URLlbry://@HealthTech#5/Talk1_GR_IK_ICXCNIKA_FINAL#3
Claim ID3b1e10a97a8b678ac2298761a3b14ade69d489f9
256.32 MB