New Study | Drinking MORE COFFEE can Reduce the Risk of Alzheimer's Disease

2 years ago
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This is a review of a study I read out of the Edith Cowan University where a long-term study has revealed drinking higher amounts of coffee may make you less likely to develop Alzheimer's disease.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420628/
https://www.ecu.edu.au/newsroom/articles/research/latte-lovers-rejoice-coffee-could-lower-risk-of-alzheimers-diseas
https://medicaldialogues.in/neurology-neurosurgery/news/study-reveals-drinking-coffee-could-lower-risk-of-alzheimers-disease-84929#:~:text=A%20new%20study%20has%20revealed%20that%20drinking%20higher,key%20factor%20in%20the%20development%20of%20Alzheimer%27s%20disease.

As part of the Australian Imaging, Biomarkers and Lifestyle Study of aging, researchers from Edith Cowan University in Perth Western Australia investigated whether coffee intake affected the rate of cognitive decline of more than 200 Australians over a decade.
Lead investigator Dr. Samantha Gardener a Post-Doctoral Research Fellow at Edith Cowan University said: “Results showed an association between coffee and several important markers related to Alzheimer's disease.
We found participants with no memory impairments and with higher coffee consumption at the start of the study had lower risk of transitioning to mild cognitive impairment, which often precedes Alzheimer's disease, or developing Alzheimer's disease over the course of the study."
Drinking more coffee gave positive results in relation to certain domains of cognitive function, specifically executive function which includes planning, self-control, and attention.
Higher coffee intake also seemed to be linked to slowing the accumulation of the amyloid protein in the brain, a key factor in the development of Alzheimer's disease.
Dr. Samantha Gardener PhD said that “Although further research was needed, the study was encouraging as it indicated drinking coffee could be an easy way to help delay the onset of Alzheimer's disease. It's a simple thing that people can change. It could be particularly useful for people who are at risk of cognitive decline but haven't developed any symptoms. We might be able to develop some clear guidelines people can follow in middle age and hopefully it could then have a lasting effect."
If you only allow yourself one cup of coffee a day, the study indicates you might be better off treating yourself to an extra cup, although a maximum number of cups per day that provided a beneficial effect was not able to be established from the current study.
In Alzheimer's disease, the amyloid clumps together forming plaques which are toxic to the brain. The study was unable to differentiate between caffeinated and de-caffeinated coffee, nor the benefits or consequences of how it was prepared (brewing method, the presence of milk and/or sugar etc.).  
"Crude caffeine" is the by-product of de-caffeinating coffee and has been shown to be as effective in partially preventing memory impairment in mice, while other coffee components, have also been seen to affect cognitive impairment in animals in various studies.
So, this study says if you drink one, going up to 2 may well help
A quick search on Microsoft Bing came up with this from the FDA and the Mayo clinic - 400 milligrams a day seems to be the agreed limit, the FDA say that’s about 4 or 5 cups and the Mayo Clinic say that’s roughly 4, of course there are so many variables when it comes to brew strength and cup size it would be difficult to state a single number when it comes to how many cups a day.
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#CAFFEINE #COFFEE #DECAF

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