Covid pandemic, good news
CDC variant report
https://covid.cdc.gov/covid-data-tracker/#variant-proportions
Some increase in BA.4.6 and BA.2.75
BA.4.6
Progressive US increase, starting to slowly displace BA.5
US of America (9,526)
Canada (1,007)
Denmark (500)
France (400)
Australia (288)
Germany (248)
Chile (242)
Dominican Republic (173), Peru (149), Luxembourg (123), Belgium (102), Israel (101), Italy (94), Ireland (93), Sweden (92), Spain (85), Netherlands (84), Brazil (76), Argentina (68), Japan (67), New Zealand (60), Switzerland (54), Puerto Rico (53), South Africa (53), Ecuador (49), Mexico (35), Colombia (34), Trinidad and Tobago (30), Czech Republic (27), Costa Rica (23), Jamaica (21), Portugal (20), South Korea (19), Austria (17), Botswana (17), Indonesia (13), Sint Maarten (12), Senegal (11)
BA.2.75
Some US increase
Growth rate is currently 61% per week relative to co-circulating lineages
Current US nowcast
BA.5 84.8% (UK, 87.2%)
BA.4.6 10.3% (UK, 3.3)
BA.4 1.8%
BF.7 1.7%
BA.2.75 1.3% (UK, 1.6%)
BA.2 0% (UK, 0.5%)
BA.1s 0%
Delta 0%
Others 0% (UK, 2.4%)
XE 0%
UK, technical briefing 45
(September 2022)
Contains early data and analysis on emerging variants
Findings have a high level of uncertainty
Data cut-off of 5 September 2022
BA.5
BA.5 is the predominant circulating variant in the United Kingdom
Newly designated variant – V-22SEP-01 (BA.4.6)
Omicron sub-lineage BA.4.6
An apparent small growth advantage relative to BA.5.
BA.4.6 represented 3.31% of UK samples
Preliminary neutralisation data from BA.4.6
Expect some immune escape from BA.4 or BA.5 antibodies
Expect some immune escape triple dosed recipients of the Pfizer BNT162b2 vaccine.
V-22JUL-01 (BA.2.75)
As of 6 September 2022
BA.2.75 in the UK, 1.6%
Does seem to have growth advantage over co-circulating lineages of,
61% per week
Two sub-lineages of BA.2.75 (BA.2.75.1 and BA.2.75.2) are currently being assessed
BA.4/BA.5 Severity
A case-control study
Risk of being admitted to hospital as an inpatient
Among people presenting to emergency care within 14 days of positive test.
Comparison, risk of admission with BA.4 or BA.5 versus BA.2
Between 16 March 2022 and 23 August 2022
BA.4 n = 2,530
BA.5 n = 12,026
BA.2 n = 17,022
Adjusted for age, sex, vaccination status, week of test, 2 days of extreme heat
There was no difference in the risk of admission between people infected with BA.4 compared to BA.2
There was no difference in the risk of admission between people infected with BA.5 compared to BA.2
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