Betaine

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Betaine is a natural substance found in dietary sources such as beets, spinach, seafoods, wheat bran, and wine. In the body, it is naturally synthesized through the metabolism of choline. Betaine can also be taken as a supplement. This potent compound possesses wide biological properties that contribute to its therapeutic activities. Betaine is often utilized in the treatment of homocystinuria and hyperhomocysteinemia, conditions characterized by high levels of homocysteine in the blood and urine, which is associated with elevated risk for the development of cardiovascular diseases. Betaine increases the levels of methionine by donating methyl groups to the toxic metabolite homocysteine, converting it into methionine. Methionine is a sulfur-containing amino acid that can be used to build proteins, but it also acts as an endogenous antioxidant. To lower the homocysteine levels in the blood, Betaine should be taken alongside other food supplements like folic acid, vitamin B12, and vitamin B6. Betaine administration is also taken for the prevention of non-alcoholic fatty liver disease or NAFLD. NAFLD is characterized primarily by the storage of excess macrovesicular fat. It is usually caused by insulin resistance and overweight. Betaine improves NAFLD mainly by preventing the accumulation of lipids in the liver and reversing insulin resistance, which is a major contributor to the disease progression. Betaine also prevents oxidative stress and inflammation in alcoholic liver disease by improving oxyradical scavenging activity in liver tissues. Moreover, it also reduces the elevation of ALT and AST in serum. Betaine also improves intestinal functions by maintaining intestinal epithelial barrier integrity. The intestinal epithelial barrier is mainly provided by a tight junctional complex, located at the apical end of epithelial cells. If this barrier is breached, it can cause inflammation and liver damage if sustained. Betaine can also significantly improve body composition, muscle endurance, and resistance training performance by aiding hydration when mixed with electrolytes. Hydration is necessary for your muscles to keep going further. It's important to talk to your doctor or other professional before beginning any sort of supplementation or treatments. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
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