Triglyceride levels and Alzheimer's disease

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Triglyceride levels and Alzheimer's disease
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In this video we will talk about how getting your cholesterol monitored at your thirties could help you prevent Alzheimer's disease later in life. Data from several studies have evidenced that serum triglyceride level is associated with the risk of cognitive impairment later in life. A study published in Neurology journal in 2020 has found that persons with mild cognitive impairment with hippocampal and entorhinal cortical atrophy have decreased triglyceride levels--long-chain polyunsaturated fatty acid-containing triglycerides or PUFA. One category of PUFA, the Omega 3 fatty acids have been proven to have beneficial functions in the brain. There are three main types of omega 3 fatty acids - alpha-linolenic acid or ALA, eicosapentaenoic acid or EPA, and docosahexaenoic acid or DHA. DHA plays a crucial role in regulating neural gene expression. Patients with Alzheimer's disease and cognitive impairment have significantly lower DHA levels in the blood plasma and brain. DHA has been shown to activate protein kinase B or Akt, via an increase in phosphatidylserine. Akt signalling activation can increase BDNF, which strengthens synaptic plasticity and cell survival. Animal studies have shown that deficiency of DHA in neural tissue leads to behavioral deficits, neurodegeneration and cognitive dysfunction similar to that in patients with Alzheimer's disease.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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