IGF-1 and sarcopenia

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IGF-1 and sarcopenia
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Insulin-like growth factor 1 or IGF-1 is a polypeptide hormone that is naturally produced by the liver and muscle. IGF-1 exerts antiapoptotic, metabolic, mitogenic, and differentiating effects. IGF-1 is an important growth hormone during childhood, because it promotes normal growth of bones and tissues. Animal studies have shown that IGF-1 also plays an important role in preventing sarcopenia in adults. Sarcopenia is characterized by the progressive decline of muscle mass and strength caused by multiple molecular and cellular changes such as a decline in mitochondrial function, increased inflammatory mediators, and increased reactive oxygen species. IGF-1 has been shown to compensate the increased in reactive oxygen species by the modulation of energy sensors AMPK and of markers of antioxidant activity such as PGC-1 alpha. We would like to hear about your own experience with this topic. Leave a comment. If you have any friends who may find this information helpful or interesting, you can use the share button and share this video with them on Facebook, Twitter, WhatsApp, or any other social media. Lastly, remember that it is important to talk to your doctor or other professional before beginning any sort of supplementation or treatments. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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