YOU HAVE TO ACTIVATE AMPK! What is AMPK and why people in longevity science speak so much about it

2 years ago
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What is AMPK and why people in longevity science speak so much about it
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AMP-activated protein kinase (AMPK) is a protein that is activated by exercise, fasting, and calorie restriction. It is an enzyme that regulates the metabolic pathways in the body. AMPK has been shown to have a positive effect on longevity and aging.AMPK activation leads to an increase in the production of ATP and a decrease in the production of glucose.AMPK activation also leads to an increase in autophagy, which is the process by which cells recycle their own components. This process helps cells maintain their health and function during periods of starvation or other low-energy conditions.The activation of AMPK has been shown to increase lonjévity in animals and humans. It also has been shown to have anti-aging effects on the brain and other organs.Activated AMPK acutely triggers the destruction of existing defective mitochondria via ULK1-dependent mitophagy and simultaneously triggers the biogenesis of new mitochondria via effects on PGC-1a dependent transcription.As far as it concerns the activation of AMPK with exercise, AMPK is activated in an intensity-dependent manner, such that its activation is usually observed acutely at exercise intensities above 60% of maximal aerobic capacity.AMPK can also be activated by some foods like blueberries, grapefruit and green tea.Multiple supplements play also a role in AMPK activation.For example, berberine significantly activates AMPK and mitigates the effects of high glucose.We would like to hear about your own experience with this topic. Leave a comment. Lastly, remember that it is important to talk to your doctor or other professional before beginning any sort of supplementation or treatment. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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