DOM D’AGOSTINO 1 | KETONES are the PREFERRED FUEL for the BRAIN

http://www.DoctorsToTrust.com
presents episode 461 | Dr Dom D’Agostino
IHMC podcast

Fasting is a way to cure epilepsy...
-Dr George Cahill: research on brain metabolism during starvation
-brain can use ketones
for energy!
-prior to this Harvard
1967 study, it was
thought that the brain
could ONLY BURN
GLUCOSE

Study: medical students, overweight, fasted for 40 days...
-after a week, blood ketones skyrocketed, and actually
-exceeded the level of glucose
-ketones become the
PREDOMINANT FUEL
for the brain during
starvation (or fasting)

Starvation
-not eating food and have no body fat reserves for fuel

Fasting
-not eating food while having body fat reserves for fuel

*today, we would call the Harvard study a 'fasting' study

When eating typical western food, including carbohydrates...
-nearly 100% of our brain energy comes from glucose
-but, in starvation (fasting) about two-thirds energy is from ketones
-ketones are the fuel for the
brain when glucose is
not available

When given a choice of fuels, the brain prefers ketones over glucose...
-Dr Ben Bikman

Keto eating can mimic fasting: it can elevate ketones while
-lowering glucose
-must restrict carbs,
-and eat lots of fat
Free fatty acids from diet
& from our adipose tissue
-processed in liver through
beta oxidation to form
ketone bodies
-must deplete liver
glycogen some &
suppress insulin

Ketones: very efficient, high energy fuel for brain and heart...
-and for skeletal muscle and skin

When kids are refractory to epileptic drugs, keto dieting prevents seizures
-it is standard of care when drugs fail
"It is a grossly underutilized
approach because it is
so effective!"
-it is not prescribed
very often

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doctorstotrust.com
ketonutrition.org

Original Youtube: https://youtu.be/RyB3VI0vwKA
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