Dietrich Stephan on NeuBase Therapeutics (NBSE) & Treating Genetic Diseases

Dr. Dietrich Stephan is a geneticist, entrepreneur, and CEO of NeuBase Therapeutics. Neubase is biotech startup focused on developing precision genetic medicines.

Dietrich previously founded or co-founded 14 biotechnology companies, was the chair of the Human Genetics department at the University of Pittsburgh, and was the CEO of LifeX Labs, a biotechnology incubator.

Neubase, his latest company, is developing technology spun out of Carnegie Mellon University that aims to address genetic diseases at the DNA or RNA level by combining the highly targeted approach of traditional genetic therapies with the broad organ distribution capabilities of small molecules.

In April 2021 Neubase went public, trading under the ticker symbol NBSE, and has raised over $100 million in less than three years.

In this conversation, Dietrich and Aaron discuss why Neubase went public earlier than most biotech startups, the vicious diseases they are fighting against, and the impact of the Human Genome Project on society.

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Dietrich Stephan’s Challenge:

Connect with Dietrich Stephan
Linkedin
https://www.linkedin.com/in/dietrich-stephan-7902178/
Neubase Website
https://www.neubasetherapeutics.com/

If you liked this interview, check out the episode with Craig Markovitz where we discuss business building, university technology transfer, and life after a successful startup.

Time Stamps
00:00 Interview with Neubase CEO Dietrich Stephan
01:20 What is the Human Genome Project?
08:52 Starting Neubase
16:41 Taking a biotech company public and de-risking
30:17 What diseases Neubase is fighting
34:01 A biology lesson in DNA
37:07 Building blocks for new biotechnology
41:19 The role of a Chief Medical Officer
45:47 Trialing these biotech methods on subjects
50:57 Dietrich's Actionable Personal Challenge

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