Chronic Fatigue Syndrome (CFS) - the FATIGUE STATE criterias - conflation, misinformation & disinformation, misdiagnosis & non-diagnosis

Epidemic Myalgic Encephalomyelopathy https://medical-dictionary.thefreedictionary.com/epidemic+myalgic+encephalomyelopathy a disease superficially resembling poliomyelitis, characterized by diffuse involvement of the nervous system associated with myalgia. Myalgic Encephalomyelitis (M.E.) https://www.thefreedictionary.com/myalgic+encephalomyelitis A condition of fatigue, malaise, and stress. It's cause is an "enteroviral infection" but it may be associated with recent "lung or stomach infection" Myalgic Encephalomyelitis (M.E.), a chronic disease causing "muscle weakness and cognitive dysfunction". Myalgic Encephalomyelitis (M.E.), identified as a new clinical entity with distinctive features in 1956, was originally considered as a neuromuscular disease. In 1988 the Centers for Disease Control and Prevention introduced the ill-defined concept of Chronic Fatigue Syndrome (CFS). As predicted, CFS, unjustly considered to be a synonym for M.E., pushed M.E. to the background. To develop effective therapies for of M.E. and CFS, it is essential to investigate patients with M.E. specifically. For that reason, an operational definition of M.E. is indispensable. This article proposes an operational definition based on the most recent formal definitions and symptoms observed in M.E. This article proposes an operational definition based on the most recent formal definitions and symptoms observed in M.E. M.E. is a multi-systemic illness, which (1) often has a sudden onset, in most cases a respiratory and/or gastro-intestinal infection (2) has an epidemic and an endemic form; (3) has an unique clinical pattern deviating from other post-viral states; (4) is distinguished by muscle fatigability/prolonged muscle weakness after trivial exertion; (5) is accompanied by symptoms relating to neurological disturbance, especially of cognitive, autonomic, and sensory functions; (6) can be accompanied by symptoms associated with cardiac and other systems; (7) is characterized by fluctuation of symptoms (within and between "episodes"); (8) has a prolonged relapsing course; and (9) has a tendency to become chronic. In conclusion, a discriminative definition for M.E. contains four mandatory elements: (1) muscle fatigability/post-exertional muscle weakness lasting for days; (2) operational criteria for "neurological disturbance, especially of cognitive, autonomic and sensory functions"; (3) fluctuation of symptoms; and (4) a prolonged relapsing course. This tentative definition of M.E. justifies the qualification "neuromuscular disease".

https://me-pedia.org/wiki/Ampligen